(A&E) (GP)

Overview

• Conditions caused by hypersensitivity of the immune system to typically harmless substances

• IgE binds to receptor on mast cell or basophil, triggering release of histamine

• Causes → dust, foods, latex, medications, insect stings, genetics, stress

• Amboss Overview

• Type 1-4 Hypersensitivity Reactions

Making Diagnosis

Clinical Features:

• Runny Nose & Sneezing
• Redness & Itching of Eyes
• Coughing & Wheezing
• Rashes & Hives (Urticaria)

Investigations: